The masterpieces that spring from the talents of Rembrandt, Van Gogh and other artists often begin with the creation of a gradient of colors on a palette. In a similar manner, researchers at the National Institute of Standards and Technology (NIST) have created an innovative device called the "microfluidic palette" to produce multiple, steady-state chemical gradientsâ€"gradual changes in concentration across an areaâ€"in a miniature chamber about the diameter of a pinhead. The tool can be used to study the complex biological mechanisms in cells responsible for cancer metastasis, wound healing, biofilm formation and other fluid-related processes.
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